X-ray User Group Meeting |
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X-ray User Group Meetings Schedule Aug 25: Yonghong Zhao Sept 28: SCSB Celebration (Tues) Oct 27: Nov 24: Dec 29: Happy New Year |
When: August 25th at 11am Where: in BSB 2.240 What: Hsp31, An example of the use of MIRAS for structure solution. A combination of heavy metal derivatives, and enhanced anomalous scattering was used to solve the Hsp31 structure and then to identify a bound Zn ion. Who: Yonghong Zhao Contact: Dr. Mark A. White white@xray.utmb.edu |
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SCSB Crystallography News |
Problem with DIP2030 Detector Solved: Over the last month the Mac Science DIP2030 detector system has has intermittent periods of failure, sometimes stopping or producing rotated images. I dismantled the detector and ran tests on the unit. Eventually, I was able to recreate the errors and trace the problems to a single cause: a worn mechanical component which locks the Image plate into position. Replacement of the worn component has solved both of the problems. The detector is now functioning perfectly. MOSFLM, PHASER and CCP4-5.0.1 are now installed and operational on our Linux workstations. HKL2000 will be available soon. Why wait two weeks? Skip the queue! The waiting list for the DIP2030 detector, equipped with the new MSC Blue confocal optics is now averaging two weeks. The SMART2K CCD detector system, which still has the older Gobel optics, is available for larger crystals (> 0.2mm) which diffract reasonably well. So don't wait, hop on the CCD, the queue is much shorter. Recent SCSB Crystallography Publications Emily E. Scott, Mark A. White, You Ai He, Eric F. Johnson, C. David Stout, and James R. Halpert, Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9 A resolution: Insight into the range of P450 conformations and coordination of redox partner binding J. Biol. Chem 279, 26, 27294-301, 2004.(PDF) |
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X-ray Crystallography Reading List – Aug (Available from the MML via ILLIAD) (See more at Acta Cryst. D) |
Acta Cryst. (2004). D60, 1355-1363 [ DOI 10.1107/S0907444904011679 ], PRODRG: a tool for high-throughput crystallography of protein-ligand complexes, A. W. Schüttelkopf and D. M. F. van AaltenActa Cryst. (2004). D60, 1413-1416 [ DOI 10.1107/S0907444904013678 ], Spectacular improvement of X-ray diffraction through fast desiccation of protein crystals, C. AbergelActa Cryst. (2004). D60, 1506-1508 [ DOI 10.1107/S0907444904011710 ], Heavy-atom derivatives in lipidic cubic phases: results on hen egg-white lysozyme tetragonal derivative crystals with Gd-HPDO3A complex, É. Girard, E. Pebay-Peyroula, J. Vicat and R. KahnJ.
Appl. Cryst. (2004). 37, 555-564,
The role of wavelength and source in the search for sulfur-atom
positions evaluated in two case studies: lysozyme at room
temperature and cryo apocrustacyanin A1, M. Cianci, J. R.
Helliwell, D. Moorcroft, A. Olczak, J. Raftery and P. J.
Rizkallah ( |
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European Crystallographic Meeting: Aug. 26-31, 2004, Budapest (Info) Eleanor & Guy Dodson Symposium: Sept. 10-12, 2004,York (UK) (Info) Structural Biology Symposium: Sept. 15-18, 2004, Hamburg (Info) Rigaku/MSC Crystallography Course: September 15-17, 2004, Houston (info) EMBL: 15-18 Sept. 2004, (DESY) Hamburg (info) SPINE: 18-19 Oct. 2004, London, UK (info ) SouthWestern Macromolecular: Oct. 22-24, 2004, Houston. (info) EMBO: 10-13 Nov. 2004, Heidelberg, DL (info) Protein Crystallography in Drug Discovery: 17-19 Jan., 2005, SF, CA (info) ACA: May 28-June 2, 2005, Orlando, Florida. (Info) IuCr XX: 23-21 Aug. 2005, Florence, Italy. (info) |
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CAMD - PX1 Beam Time |
August 23 - 25th 2004
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Time begins at noon of 1st day. Radiation Safety - PX1 – Ring Current – Directions – Hotels and Restaurants (PX1 225.578.7137) – Contacts: UTMB - CAMD |
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Let The SCSB Advance Your Research |
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The SCSB is here to facilitate your Structural Biology research. |
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Research Areas |
Expertise |
Meetings |
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User Training |
The SCSB staff is always ready and happy to train your students, post-docs and technicians in the correct use of the SCSB Instrumentation. They will also pick-up a few helpful hints along the way also. The support of the SCSB and the assistance by the staff member(s) should be acknowledged in any publications. |
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Mentoring |
If you do not have the expertise to perform certain types of research the SCSB staff or faculty may be able to mentor your graduate student or post-doc as a collaborative project. Mentoring requires a significant commitment by both the mentor and student learning a new field of research. The Mentor should be co-author on any publications resulting from the student's research project. The support of the SCSB should be acknowledged in any publications. |
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Collaborations |
Please contact any SCSB researcher (PI) or Core Manager to discuss possible collaborate research projects. Of course such projects are at the discretion and time-restraints of the collaborator. The Collaborator should be an author on any publications resulting from the collaborative research project. The support of the SCSB should be acknowledged in any publications. |
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X-ray Group User Meetings |
When: Last Wednesday of each month. Where: BSB 2.240. When: 11 am. Why: To discuss all aspects of crystallography. What: A small group meeting and informal presentation. Who: Anyone interested in crystallography. How: Contact Dr. Mark A. White white@xray.utmb.edu |
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