X-ray User Group Meeting




X-ray User Group Meetings

Schedule

Aug 25: Yonghong Zhao

Sept 28: SCSB Celebration (Tues)

Oct 27:

Nov 24:

Dec 29: Happy New Year

When: August 25th at 11am

Where: in BSB 2.240

What: Hsp31, An example of the use of MIRAS for structure solution. A combination of heavy metal derivatives, and enhanced anomalous scattering was used to solve the Hsp31 structure and then to identify a bound Zn ion.

Who: Yonghong Zhao

Contact: Dr. Mark A. White white@xray.utmb.edu




SCSB Crystallography News

Problem with DIP2030 Detector Solved: Over the last month the Mac Science DIP2030 detector system has has intermittent periods of failure, sometimes stopping or producing rotated images. I dismantled the detector and ran tests on the unit. Eventually, I was able to recreate the errors and trace the problems to a single cause: a worn mechanical component which locks the Image plate into position. Replacement of the worn component has solved both of the problems. The detector is now functioning perfectly.

MOSFLM, PHASER and CCP4-5.0.1 are now installed and operational on our Linux workstations. HKL2000 will be available soon.

Why wait two weeks? Skip the queue! The waiting list for the DIP2030 detector, equipped with the new MSC Blue confocal optics is now averaging two weeks. The SMART2K CCD detector system, which still has the older Gobel optics, is available for larger crystals (> 0.2mm) which diffract reasonably well. So don't wait, hop on the CCD, the queue is much shorter.

Recent SCSB Crystallography Publications

Emily E. Scott, Mark A. White, You Ai He, Eric F. Johnson, C. David Stout, and James R. Halpert, Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9 A resolution: Insight into the range of P450 conformations and coordination of redox partner binding J. Biol. Chem 279, 26, 27294-301, 2004.(PDF)




X-ray Crystallography Reading List – Aug

(Available from the MML via ILLIAD)

(See more at Acta Cryst. D)

Acta Cryst. (2004). D60, 1355-1363 [ DOI 10.1107/S0907444904011679 ], PRODRG: a tool for high-throughput crystallography of protein-ligand complexes, A. W. Schüttelkopf and D. M. F. van Aalten

Acta Cryst. (2004). D60, 1413-1416 [ DOI 10.1107/S0907444904013678 ], Spectacular improvement of X-ray diffraction through fast desiccation of protein crystals, C. Abergel

Acta Cryst. (2004). D60, 1506-1508 [ DOI 10.1107/S0907444904011710 ], Heavy-atom derivatives in lipidic cubic phases: results on hen egg-white lysozyme tetragonal derivative crystals with Gd-HPDO3A complex, É. Girard, E. Pebay-Peyroula, J. Vicat and R. Kahn

J. Appl. Cryst. (2004). 37, 555-564, The role of wavelength and source in the search for sulfur-atom positions evaluated in two case studies: lysozyme at room temperature and cryo apocrustacyanin A1, M. Cianci, J. R. Helliwell, D. Moorcroft, A. Olczak, J. Raftery and P. J. Rizkallah ([PDF version])




Crystallographic Meetings (IUCr) (ACA) (BCA)

European Crystallographic Meeting: Aug. 26-31, 2004, Budapest (Info)

Eleanor & Guy Dodson Symposium: Sept. 10-12, 2004,York (UK) (Info)

Structural Biology Symposium: Sept. 15-18, 2004, Hamburg (Info)

Rigaku/MSC Crystallography Course: September 15-17, 2004, Houston (info)

EMBL: 15-18 Sept. 2004, (DESY) Hamburg (info)

SPINE: 18-19 Oct. 2004, London, UK (info )

SouthWestern Macromolecular: Oct. 22-24, 2004, Houston. (info)

EMBO: 10-13 Nov. 2004, Heidelberg, DL (info)

Protein Crystallography in Drug Discovery: 17-19 Jan., 2005, SF, CA (info)

ACA: May 28-June 2, 2005, Orlando, Florida. (Info)

IuCr XX: 23-21 Aug. 2005, Florence, Italy. (info)




CAMD - PX1

Beam Time

August 23 - 25th 2004


Time begins at noon of 1st day. Radiation Safety - PX1Ring Current – Directions – Hotels and Restaurants (PX1 225.578.7137) – Contacts: UTMB - CAMD







Let The SCSB Advance Your Research



The SCSB is here to facilitate your Structural Biology research.

Research Areas

Expertise

Meetings

  • User Training

  • Mentoring

  • Collaborations






User Training

The SCSB staff is always ready and happy to train your students, post-docs and technicians in the correct use of the SCSB Instrumentation. They will also pick-up a few helpful hints along the way also. The support of the SCSB and the assistance by the staff member(s) should be acknowledged in any publications.

Mentoring

If you do not have the expertise to perform certain types of research the SCSB staff or faculty may be able to mentor your graduate student or post-doc as a collaborative project. Mentoring requires a significant commitment by both the mentor and student learning a new field of research. The Mentor should be co-author on any publications resulting from the student's research project. The support of the SCSB should be acknowledged in any publications.

Collaborations

Please contact any SCSB researcher (PI) or Core Manager to discuss possible collaborate research projects. Of course such projects are at the discretion and time-restraints of the collaborator. The Collaborator should be an author on any publications resulting from the collaborative research project. The support of the SCSB should be acknowledged in any publications.






X-ray Group User Meetings

When: Last Wednesday of each month.

Where: BSB 2.240.

When: 11 am.

Why: To discuss all aspects of crystallography.

What: A small group meeting and informal presentation.

Who: Anyone interested in crystallography.

How: Contact Dr. Mark A. White white@xray.utmb.edu